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In normal epithelial tissues, the intracellular maspin is predominantly nuclear. Representative genes and pathways affecting multimetal tolerance as well as a subset of co-clustering uncharacterized open reading frames with orthologous sequences in other organisms (see Additional data file 2) are indicated on the right-hand and left-hand, respectively.

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Department of Neurobiology, Barrow Neurological Institute, Phoenix, AZ, United States of America, Department of Neurobiology, Barrow Neurological Institute, Phoenix, AZ, United States of America, Department of Neurobiology, Barrow Neurological Institute, Phoenix, AZ, United States of America.
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Their proportion was higher than the expected false positive rate in each of the analyzed nuclei (binomial test, p Figure S1.

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